Glutathione is often called the body’s master antioxidant, and for good reason. It plays a central role in protecting cells from damage caused by oxidative stress, a process linked to ageing, inflammation, weakened immunity, and chronic fatigue. Understanding how glutathione works and why the delivery method matters can help explain why it has become a cornerstone of modern IV therapy.
What Is Oxidative Stress
Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body. Free radicals are unstable molecules produced through normal metabolism, pollution exposure, stress, alcohol consumption, and poor sleep. When antioxidant defences are overwhelmed, these molecules begin to damage cells, proteins, and DNA.
Over time, unmanaged oxidative stress is associated with premature ageing, reduced energy levels, dull skin, slower recovery, and compromised immune response.
The Role of Glutathione in the Body
Glutathione is a naturally occurring antioxidant produced in the liver and present in every cell. Unlike many antioxidants obtained through diet, glutathione works at a cellular level. Its primary functions include:
- Neutralising free radicals and reducing oxidative damage
- Supporting liver detoxification pathways
- Maintaining immune system efficiency
- Recycling other antioxidants, such as vitamins C and E
Low glutathione levels have been linked to increased fatigue, inflammation, slower recovery, and reduced resilience to environmental stressors.
Why Glutathione Levels Decline
Despite its importance, glutathione levels decline with age. Chronic stress, poor diet, illness, pollution exposure, alcohol intake, and intense physical exertion all increase glutathione demand. In many individuals, the body struggles to replenish optimal levels through natural production alone.
This is where supplementation becomes relevant. However, oral glutathione has limited absorption due to breakdown in the digestive system.
Why IV Glutathione Is Often Preferred
IV glutathione therapy bypasses digestion entirely, delivering glutathione directly into the bloodstream. This allows for significantly higher bioavailability compared to oral supplements. IV delivery ensures that glutathione reaches cells efficiently, where it can actively reduce oxidative stress and support detoxification.
Many individuals choose glutathione IV therapy to support skin clarity, immune health, recovery, and overall cellular protection. Results are typically gradual and cumulative rather than instant, reflecting true physiological support rather than surface-level effects.
A Clinical Approach to Antioxidant Support
Medical oversight is essential when administering antioxidants intravenously. Dosage, formulation, and infusion protocols must be tailored to individual needs to ensure safety and effectiveness.
At REVIV, glutathione protocols are doctor-led and designed to support cellular health without overloading the body. This medical approach ensures antioxidant therapy works in harmony with natural biological processes.
Glutathione remains one of the most powerful tools for managing oxidative stress. When delivered correctly, it supports long-term health at the cellular level rather than offering temporary cosmetic benefits.

